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Clinical trials for Third Molar

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    35 result(s) found for: Third Molar. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2014-000996-18 Sponsor Protocol Number: FJQ-BUP-2014-01 Start Date*: 2015-04-23
    Sponsor Name:Complejo Hospitalario Torrecárdenas
    Full Title: CLINICAL TRIAL TO EVALUATE THE EFFICACY AND THE SECURITY OF DEXAMETASONE+BUPIBACAINE+ARTICAINE+EPINEFRINE “VERSUS” ARTICAINE+EPINEFRINE IN THE POSTQUIRURGICAL PAIN OF THIRD MOLAR SURGERY
    Medical condition: THIRD MOLAR REMOVING
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000736-25 Sponsor Protocol Number: IB3M.2019 Start Date*: 2019-09-05
    Sponsor Name:Universidad Complutense de Madrid
    Full Title: Efficacy of Non-Steroidal Anti-Inflammatory (Ibuprofen) Chronotherapy in Healing After Mandibular Third Molar Surgical Extraction – A Randomized Clinical Trial
    Medical condition: The clinical trial will try to understand if the elimination of the ibuprofen dosage in resting phase after surgical third molar extraction not jeopardize the postoperative period .
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000193-77 Sponsor Protocol Number: 05/Q1405/78 Start Date*: 2007-03-20
    Sponsor Name:The University of Manchester
    Full Title: Protective analgesia using bupivacaine and conventional release ibuprofen versus bupivacaine and sustained release ibuprofen for postoperative pain relief in patients undergoing third molar surgery...
    Medical condition: Pain following surgical removal of impacted lower wisdom tooth/ teeth.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004682-24 Sponsor Protocol Number: DC0071BB405 Start Date*: 2015-04-27
    Sponsor Name:Institut de Recherche Pierre Fabre - Centre de R&D Pierre Fabre
    Full Title: Efficacy of DC071 mouthwash (0,2 % chlorhexidine digluconate) in peri-surgical care for preventing alveolar osteitis after third molar extraction. Prospective, multicenter, randomised, double-blin...
    Medical condition: Prevention of alveolar osteitis after third molar extraction
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021881 - Infections and infestations 10066995 Alveolar osteitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: EE (Completed) LV (Completed) LT (Completed) FR (Completed) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004083-62 Sponsor Protocol Number: steroid3848 Start Date*: 2019-09-06
    Sponsor Name:Semmelweis University, Oro-Maxillofacial Surgery and Stomatology
    Full Title: Effect of preoperative intramasseteric methylprednisolone injection on the post-operative sequelae of lower third molar surgery: a placebo controlled, randomized, double-blinded study
    Medical condition: post-operative swelling, trismus, pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-000622-35 Sponsor Protocol Number: 56872 Start Date*: 2017-10-23
    Sponsor Name:Aalborg University Hospital
    Full Title: Different dosis of corticosteroids in mandibular third molar surgery. A randomized, blinded clinical trial assessing pain, trismus, edema, and quality of life outcome measurements.
    Medical condition: The purpose is to investigate the postoperative morbidity after removal of mandibular third molar with different doses of methylprednisolone.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004863 10036278 Postoperative complications NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-000901-31 Sponsor Protocol Number: 18122006 Start Date*: 2007-05-15
    Sponsor Name:Universitair Ziekenhuis Antwerpen
    Full Title: A DOUBLE-BLIND? PLACEBO-CONTROLLED PARALLEL ARM TRIAL TO STUDY THE EFFICACY OF A SINGLE ORAL DOSE OF THE NUCLEOSIDE TRANSPORT INHIBITOR DIPYRIDAMOLE FOR PAIN RELIEF IN PATIENTS AFTER THIRD MOLAR SU...
    Medical condition: Pain after third molar surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-003258-21 Sponsor Protocol Number: PDC-01-0205 Start Date*: 2022-05-19
    Sponsor Name:Cessatech A/S
    Full Title: Analgesic Efficacy and Pharmacokinetic-pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001 after Impacted Mandibular Third Molar Extraction
    Medical condition: Healthy male or female participants scheduled for surgical removal of an impacted mandibular third molar, where bone removal is judged to be needed.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004865 10050327 Dental surgery NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002784-27 Sponsor Protocol Number: Stei-Azurcomp-0107 Start Date*: 2008-01-18
    Sponsor Name:Steiner & Co. Deutsche Arzneimittelgesellschaft mbH & Co. KG
    Full Title: Randomised, double-blind, prospective multi-centre study to compare the analgesic efficacy and safety of a paracetamol/codeine/caffeine fixed-dose combination (Azur® compositum) with paracetamol/co...
    Medical condition: Post-operative pain after a dental surgical procedure (third molar surgery).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003976-20 Sponsor Protocol Number: GRC6211-201 Start Date*: 2007-09-12
    Sponsor Name:GLENMARK PHARMACEUTICALS SA
    Full Title: A randomised, double blind, placebo and active controlled, parallel group study to evaluate the analgesic effect of a single dose of GRC 6211, a TRPV1 receptor antagonist on pain following third...
    Medical condition: treatment of pain following third molar extraction
    Disease: Version SOC Term Classification Code Term Level
    10056350 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-000902-31 Sponsor Protocol Number: ECACOR19 Start Date*: 2019-09-05
    Sponsor Name:OMEQUI
    Full Title: Healing efficacy after impacted mandibular third molar surgery with the use of autologous platelet-rich fibrin: a randomized controlled clinical study
    Medical condition: If the addition of L-PRF reduces postoperative pain and inflammation, as well as complications, after extraction of lower third molars
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000200-14 Sponsor Protocol Number: Start Date*: 2005-07-08
    Sponsor Name:North Bristol NHS Trust
    Full Title: A randomised, double-blinded comparison of the effectiveness of intravenously administered Ketoralac versus Dexamethasone in the treatment of pain following surgical removal of third molar teeth un...
    Medical condition: Pain experienced after the surgical removal of impacted third molars.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005478-66 Sponsor Protocol Number: PDY5808 Start Date*: 2006-02-09
    Sponsor Name:Sanofi-Synthelabo Recherche
    Full Title: Effect of a single oral 120 µg dose of SSR150106XB compared to placebo on the assessment of post dental surgical pain after extraction of an impacted or partially impacted third molar in 90 male an...
    Medical condition: Men and women who are to undergo elective surgery for extraction of at least one lower impacted or partially impacted third molar
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059723 LLTn
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004790-10 Sponsor Protocol Number: A2720382 Start Date*: 2007-06-06
    Sponsor Name:GlaxoSmithKline Consumer Healthcare
    Full Title: A Proof-of-Principle Analgesic Adjuvant Pilot Study in Post-Operative Dental Pain
    Medical condition: Analgesia induced by dental extraction
    Disease: Version SOC Term Classification Code Term Level
    8.1 10044049 Dental pain and sensation disorders HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-002691-18 Sponsor Protocol Number: CBA106809 Start Date*: 2006-10-03
    Sponsor Name:GlaxoSmithKline Research & Development
    Full Title: A multi-centre, randomised, single-blind, placebo-controlled, parallel group study to investigate the efficacy of single pre-emptive doses of GW842166X, a non-cannabinoid CB2 receptor agonist, on p...
    Medical condition: Inflammatory Pain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10044049 Dental pain and sensation disorders HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) IT (Completed) DE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-000535-86 Sponsor Protocol Number: HAP.2011-002 Start Date*: 2011-03-29
    Sponsor Name:CHU AMBROISE PARE
    Full Title: A PHASE IIb STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ROPIVACAINE COMPARED TO ADRENALINE-LIDOCAINE TO REDUCE PAIN IN PATIENT UNDERGOING SURGERY FOR THIRD MOLAR TEETH EXTRACTION.
    Medical condition: third molar theeth included needing surgical extraction
    Disease: Version SOC Term Classification Code Term Level
    12.1 10044039 Tooth extraction NOS LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004481-16 Sponsor Protocol Number: VRA105345 Start Date*: 2005-12-19
    Sponsor Name:GlaxoSmithKline Research and Development
    Full Title: A multi-centre, randomised, single blind, placebo controlled, parallel group study to examine the effect of single doses of SB-705498, a TRPV1 receptor antagonist, on pain following third molar too...
    Medical condition: Dental pain
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-004152-22 Sponsor Protocol Number: DEX-TRA-06 Start Date*: 2016-03-01
    Sponsor Name:MENARINI RICERCHE S.p.A.
    Full Title: Analgesic efficacy of oral dexketoprofen trometamol/tramadol hydrochloride versus tramadol hydrochloride/paracetamol: a randomised, double-blind, placebo and active-controlled, parallel group study...
    Medical condition: moderate to severe acute pain after removal of impacted lower third molar
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004867 10066714 Acute pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) HU (Completed) ES (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-000592-24 Sponsor Protocol Number: MR308-3501 Start Date*: 2017-03-15
    Sponsor Name:Mundipharma Research GmbH & Co. KG
    Full Title: A Randomized, Double-Blind, Multicenter, Placebo- and active Comparator-Controlled Study to evaluate Efficacy and Safety of MR308 in the Treatment of Acute Pain After Third Molar Tooth Extraction (...
    Medical condition: Acute pain after third molar tooth extraction; dental procedure must have involved extraction of at least two impacted third molars requireing bone removal. If only two impacted third molars are ex...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000023314 10066714 Acute pain LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2013-003323-11 Sponsor Protocol Number: ITIBU001 Start Date*: 2014-10-01
    Sponsor Name:"Sapienza" University of Rome
    Full Title: RANDOMIZED CLINICAL TRIAL, PLACEBO-CONTROLLED, SPLIT-MOUTH, A DOUBLE-BLIND, FOR THE EVALUATION OF THE EFFECTIVENESS OF PREemptive ANALGESIA BY ADMINISTRATION OF IBUPROFEN 400MG, FOR THE CONTROL ...
    Medical condition: POST-OPERATIVE ACUTE PAIN (DAPO)
    Disease: Version SOC Term Classification Code Term Level
    17.1 10017947 - Gastrointestinal disorders 10031009 Oral pain PT
    17.1 10017947 - Gastrointestinal disorders 10030973 Oral discomfort PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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